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need to know
China to close market this week to honor WW II
CNN shakes up GOP debate criteria
Pope puts abortion forgiveness on the table
Survey may confirm our worst gender fears
GE names first female vice chair
Amgen finds data falsified in diabetes study

NYSE invokes Rule 48 before market open

McDonald’s set to offer all-day breakfast


 
Uber drivers lawsuit  endangers much more than Uber
Uber driver suit can proceed as class-action

Never use a market order when stocks are selling off

Texas edges out North Dakota in this oil list

Where every Fed member stands on raising rates

Rate-hike question is what Yellen didn’t want
Boston Fed president: Sept. doubt remains

New on the shelves of your local Apple Store: drones

Annie Leibovitz is working on UBS’s image

How LVMH poached Apple digital exec Ian Rogers

What to expect at September Apple event
What to expect from the Apple event on Sept. 9
Apple talks to Hollywood for exclusive content
Apple, Cisco team to put business users on iOS
Apple will let iPhone and iPad users block ads
Lost Apple deal leads to 40% job cut at GT

Yahoo CEO Marissa Mayer
Yahoo CEO Marissa Mayer pregnant with twins

Canada’s economy enters recession — arguably

Construction laborers work on the top floor of a high rise apartment building in New York.
Building is emerging as strongest sector of economy
U.S. manufacturing growth at 2-year low: ISM

How China turned minor yuan issue into global rout
Chinese factory data pull Asian shares lower
Beijing bumbling is China’s biggest problem

These are the cars that get the most Instagram attention

Best time to buy a new car may be just around the corner
U.S. car sales are stronger than expected

10 cities in U.S. with the very worst traffic problems
Lowest Labor Day gas prices in 11 years: AAA

Trump says Mount McKinley name change ‘insult to Ohio’
Trump: Switch to Denali is ‘insult to Ohio’
Mount McKinley in Alaska is renamed Denali
Which U.S. president has the tallest mountain?

Classified details blacked out in new Clinton emails
Classified details blacked out in new emails
Clinton says she supports ‘revolving door’ bill
Biden a tougher matchup than Clinton: poll

Unlucky lottery winner gets IOU from Illinois

/conga/frontpage.html 353884

Markets »

171.39MDow Volume:
Avg Vol: 111.86M
Unchanged
163
Decliners
5264
Advancers
1172
Price Chg %Chg 1 Day
Range: 1 Day
  • 1 Day
  • 5 Days
  • 1 Month
  • 3 Months
  • 6 Months
  • 1 Year
  • 2 Years
Dow
/quotes/zigman/627449/realtime 16,058 -470 2.84%
Nasdaq
/quotes/zigman/12633936/realtime 4,636 -140 2.94%
S&P 500
/quotes/zigman/3870025/realtime 1,914 -58 2.96%
GlobalDow
/quotes/zigman/629063/realtime 2,291 -4 0.18%
Gold
/quotes/zigman/662444/delayed 1,139 -1 0.11%
Oil
/quotes/zigman/2331095/delayed 44.15 -1.26 2.77%
FTSE 100
/quotes/zigman/3173262/delayed 6,059 -189 3.03%
DAX
/quotes/zigman/2380246/delayed 10,016 -244 2.38%
CAC 40
/quotes/zigman/3173214/delayed 4,541 -112 2.40%
FTSE MIB
/quotes/zigman/1482176/delayed 21,451 -491 2.24%
IBEX 35
/quotes/zigman/2759620/delayed 9,993 -266 2.59%
Stoxx 600
/quotes/zigman/2380150/delayed 353 -10 2.73%
Asia Dow
/quotes/zigman/6959860/realtime 2,697 -21 0.76%
Nikkei 225
/quotes/zigman/5986735/delayed 18,166 -725 3.84%
Hang Seng
/quotes/zigman/2622475/delayed 21,185 -485 2.24%
Shanghai
/quotes/zigman/1859015/delayed 3,167 -39 1.23%
Sensex
/quotes/zigman/1652085/delayed 25,696 -587 2.23%
Singapore
/quotes/zigman/1709939/delayed 2,883 -39 1.32%
Euro
/quotes/zigman/16008136/realtime/sampled 1.13 0.00 0.21%
Yen
/quotes/zigman/16008150/realtime/sampled 119.92 +0.55 0.46%
Pound
/quotes/zigman/16008140/realtime/sampled 1.53 0.00 0.05%
Australia$
/quotes/zigman/16008115/realtime/sampled 0.70 0.00 0.04%
DXY Index
/quotes/zigman/1652083/delayed 95.47 +0.09 0.10%
WSJ $ Idx
/quotes/zigman/41508961/realtime 88.33 +0.16 0.18%
U.S. 10yr
/quotes/zigman/15866666/realtime 2.16 +0.01 0.33%
German 10y
/quotes/zigman/15866409/realtime 0.80 +0.06 8.79%
Italy 10yr
/quotes/zigman/15866497/realtime 2.00 +0.08 4.05%
Spain 10yr
/quotes/zigman/15866444/realtime 2.14 +0.08 3.76%
U.K. 10yr
/quotes/zigman/15866328/realtime 1.83 -0.02 1.25%
Japan 10yr
/quotes/zigman/15866525/realtime 0.36 -0.02 4.88%
Crude Oil
/quotes/zigman/2331095/delayed 44 -1 2.77%
Gold
/quotes/zigman/662444/delayed 1,139 -1 0.11%
Corn
/quotes/zigman/7599553/delayed 368 -7 1.87%
DJIA F
/quotes/zigman/38649152/delayed 16,120 +33 0.21%
S&P F
/quotes/zigman/30356461/delayed 1,920 +4 0.23%
Silver
/quotes/zigman/3134148/delayed 15 0 0.27%

Quotes

Symbol Price Change % Change
FB /quotes/zigman/9962609/composite 87.23 -2.20 -2.46%
AAPL /quotes/zigman/68270/composite 107.72 -5.04 -4.47%
GOOG /quotes/zigman/30194416/composite 597.79 -20.46 -3.31%
BAC /quotes/zigman/190927/composite 15.58 -0.76 -4.65%
C /quotes/zigman/5065548/composite 50.94 -2.54 -4.75%
F /quotes/zigman/264304/composite 13.72 -0.15 -1.08%
T /quotes/zigman/398198/composite 32.32 -0.88 -2.65%
BP /quotes/zigman/247026/composite 32.14 -1.40 -4.17%
GE /quotes/zigman/227468/composite 23.88 -0.94 -3.79%
Visit the quote page and your most recently viewed stocks will automatically be displayed here.
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Rates »

5 yr CD
1.5%
2 yr CD
0.8%
1 yr CD
0.6%
MMA $10K+
0.3%
MMA $50K+
0.4%

National averages from Bankrate.com

You Don’t Need Another Credit Card, You Need A Better One.
Avg. APR Last Week 6 Months
Low Interest 11.62% 11.62% 11.53%
Business 12.85% 12.85% 12.85%
Student 13.14% 13.14% 13.14%
Balance Transfer 14.12% 14.12% 14.00%
Airline 15.10% 15.10% 15.15%
Reward 15.14% 15.14% 14.99%
Cash Back 15.27% 15.27% 15.26%
Instant Approval 18.00% 18.00% 17.93%
Bad Credit 22.73% 22.73% 22.48%
Source:CreditCards.com

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Investing in ‘Junk DNA’

Now that scientists have revealed that the huge swaths of genetic code once dismissed as “junk DNA” are not so worthless, investors may wonder if there’s similar hidden value in the biotech sector. The short answer: maybe.

Alexander Raths / Shutterstock.com

Though analysts say it’s too soon to tell what impact the discovery will have on stocks, the recent breakthrough may eventually lead to new techniques for the early detection of diseases and to the development of new drugs. And that could be a boon to firms at the forefront of biotechnology and molecular diagnostics.

Even before the findings from the project known as Encode emerged, the biotechnology sector was already on the cutting edge, at least in terms of market performance: The iShares Nasdaq Biotechnology Index ETF (IBB) is up more than 47% over the past 12 months, with double the returns of the broader S&P Healthcare Index. But this latest discovery suggests there could be even more promising returns ahead. The new understanding of junk DNA may help science-driven pharmaceutical companies figure out which genetic proteins can be treated with drugs, lead diagnostics companies to which genetic variations are red flags for certain diseases and help other firms evaluate the effectiveness of their treatments, says Dr. Thomas Gingeras, the head of functional genomics at Cold Spring Harbor Laboratory and one of the principal investigators for the Encode project.

“This junk DNA is just another layer of complexity, but it also brings us a little bit closer to having a more full set of therapies that we can bring to patients,” says Karen Andersen, a Morningstar biotechnology analyst.

It wouldn’t be the first time that what scientists once considered genetic trash turned into corporate treasure. Regulus Therapeutics, a joint venture between drug companies Alnylam Pharmaceuticals (ALNY) and Isis Pharmaceuticals (ISIS) that last month began SEC proceedings to go public, focuses entirely on treating diseases through microRNA—but a decade ago, that part of the genome was also considered junk. (Regulus declined to comment.)

The new research may also bring business to Alnylam, which uses a technique known as RNA Interference to basically turn off disease-causing genes; the data could help the company identify new disease markers for which it could develop therapies, says Barry Greene, Alnylam’s chief operating officer. “It opens up a world of biologic insight that will be helpful,” says Greene. While it may take a while for companies to apply the results, the research is a step forward that might eventually lead to companies like Regulus being formed to pursue new genetic therapies: “We’ve never written aspects of the genome off,” Greene says.

The new insight may also have positive implications for molecular diagnostics companies that are already using genomic information to test for diseases, such as Myriad Genetics (MYGN), which makes tests for evaluating how likely a person is to develop various types of cancer. Knowing more about the “junk DNA” might help the company develop more sophisticated tests to detect a disease even before it forms, says Andersen. Myriad declined to comment.

Pharmaceutical companies are also increasingly interested in harnessing our genes to create better drugs and to assess whether those drugs will work for a patient or cause side effects. A large part of the strategy at Roche (RHHBY), for example, is genetic research, which the company uses to create diagnostic tests to go along with each of its drugs, in an effort to deliver more “personalized health care.” Sixty percent of the drugs in the firm’s pipeline are now paired with a test, including treatments it is developing for schizophrenia and Alzheimer’s disease. Roche was not available to comment before press time.

Another type of genetic science known as epigenetics—which relates to how a gene is expressed—is becoming popular with pharmaceutical companies, who are using the concept to create new drugs that can virtually alter a person’s genetic instructions, says Andersen. Celgene (CELG), for one, racked up about $700 million last year in sales of its drug Vidaza, which treats some forms of anemia and leukemia by helping bone marrow produce normal blood cells instead of unhealthy ones.

Celgene executives weren’t available to comment on Encode’s implications for the company, but a spokesman said that the biotechnology industry is experiencing “a shift toward targeted therapies” such as epigenetics, and that greater understanding of genetic and cellular functions helps researchers “narrow their focus within diseases themselves” and “uncover new pathways that may lead to whole classes of therapies.”

Comments

We welcome thoughtful comments from readers. Please comply with our guidelines. Our blogs do not require the use of your real name.

Comments (5 of 11)

View all Comments »
    • En jevn bevegelse inn og ut kan gradvis tilvenne rumpa størrelsen, og så kan du øke på med noe større. Det er kun den seksuelle opplevelsen som teller og står i fokus. Til temaet er sex mulighetene mange og man kan utforske mye.

    • Det er lettest om han som er i rumpa ikke beveger seg så mye. Jeg har mine forestillinger om hva jeg leter etter og det er modne damer som er åpen for Swinger. Fokuset her er ikke på den raske, anonyme og overfladiske tilfredsstillelsen, men på et spennende møte mellom to mennesker som ønsker å dele singelsex erfaringer med hverandre.

    • Hello! I could have sworn I’ve been to this site before but after reading through some of the post I realized it’s new to me. Anyhow, I’m definitely glad I found it and I’ll be book-marking and checking back often!

    • Det er jo noen som syns det er ekkelt å ha sex i det fri og mange er redd for at det er noen som tar dem på fersken. Det er kun den seksuelle opplevelsen som teller og står i fokus. De vakre og unge menneskene fra reklamen blir ikke lenger sett på som en trussel.

    • Excellently)))))))

      _________________

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MarketWatch - Stock Market Quotes, Business News, Financial News
Bulletin
Investor Alert

Tokyo Markets Close in:

need to know
China to close market this week to honor WW II
CNN shakes up GOP debate criteria
Pope puts abortion forgiveness on the table
Survey may confirm our worst gender fears
GE names first female vice chair
Amgen finds data falsified in diabetes study

NYSE invokes Rule 48 before market open

McDonald’s set to offer all-day breakfast


 
Uber drivers lawsuit  endangers much more than Uber
Uber driver suit can proceed as class-action

Never use a market order when stocks are selling off

Texas edges out North Dakota in this oil list

Where every Fed member stands on raising rates

Rate-hike question is what Yellen didn’t want
Boston Fed president: Sept. doubt remains

New on the shelves of your local Apple Store: drones

Annie Leibovitz is working on UBS’s image

How LVMH poached Apple digital exec Ian Rogers

What to expect at September Apple event
What to expect from the Apple event on Sept. 9
Apple talks to Hollywood for exclusive content
Apple, Cisco team to put business users on iOS
Apple will let iPhone and iPad users block ads
Lost Apple deal leads to 40% job cut at GT

Yahoo CEO Marissa Mayer
Yahoo CEO Marissa Mayer pregnant with twins

Canada’s economy enters recession — arguably

Construction laborers work on the top floor of a high rise apartment building in New York.
Building is emerging as strongest sector of economy
U.S. manufacturing growth at 2-year low: ISM

How China turned minor yuan issue into global rout
Chinese factory data pull Asian shares lower
Beijing bumbling is China’s biggest problem

These are the cars that get the most Instagram attention

Best time to buy a new car may be just around the corner
U.S. car sales are stronger than expected

10 cities in U.S. with the very worst traffic problems
Lowest Labor Day gas prices in 11 years: AAA

Trump says Mount McKinley name change ‘insult to Ohio’
Trump: Switch to Denali is ‘insult to Ohio’
Mount McKinley in Alaska is renamed Denali
Which U.S. president has the tallest mountain?

Classified details blacked out in new Clinton emails
Classified details blacked out in new emails
Clinton says she supports ‘revolving door’ bill
Biden a tougher matchup than Clinton: poll

Unlucky lottery winner gets IOU from Illinois

/conga/frontpage.html 353884

Markets »

171.39MDow Volume:
Avg Vol: 111.86M
Unchanged
163
Decliners
5264
Advancers
1172
Price Chg %Chg 1 Day
Range: 1 Day
  • 1 Day
  • 5 Days
  • 1 Month
  • 3 Months
  • 6 Months
  • 1 Year
  • 2 Years
Dow
/quotes/zigman/627449/realtime 16,058 -470 2.84%
Nasdaq
/quotes/zigman/12633936/realtime 4,636 -140 2.94%
S&P 500
/quotes/zigman/3870025/realtime 1,914 -58 2.96%
GlobalDow
/quotes/zigman/629063/realtime 2,291 -4 0.18%
Gold
/quotes/zigman/662444/delayed 1,139 -1 0.10%
Oil
/quotes/zigman/2331095/delayed 44.15 -1.26 2.77%
FTSE 100
/quotes/zigman/3173262/delayed 6,059 -189 3.03%
DAX
/quotes/zigman/2380246/delayed 10,016 -244 2.38%
CAC 40
/quotes/zigman/3173214/delayed 4,541 -112 2.40%
FTSE MIB
/quotes/zigman/1482176/delayed 21,451 -491 2.24%
IBEX 35
/quotes/zigman/2759620/delayed 9,993 -266 2.59%
Stoxx 600
/quotes/zigman/2380150/delayed 353 -10 2.73%
Asia Dow
/quotes/zigman/6959860/realtime 2,697 -20 0.75%
Nikkei 225
/quotes/zigman/5986735/delayed 18,166 -725 3.84%
Hang Seng
/quotes/zigman/2622475/delayed 21,185 -485 2.24%
Shanghai
/quotes/zigman/1859015/delayed 3,167 -39 1.23%
Sensex
/quotes/zigman/1652085/delayed 25,696 -587 2.23%
Singapore
/quotes/zigman/1709939/delayed 2,883 -39 1.32%
Euro
/quotes/zigman/16008136/realtime/sampled 1.13 0.00 0.22%
Yen
/quotes/zigman/16008150/realtime/sampled 119.93 +0.56 0.47%
Pound
/quotes/zigman/16008140/realtime/sampled 1.53 0.00 0.05%
Australia$
/quotes/zigman/16008115/realtime/sampled 0.70 0.00 0.04%
DXY Index
/quotes/zigman/1652083/delayed 95.47 +0.09 0.09%
WSJ $ Idx
/quotes/zigman/41508961/realtime 88.33 +0.16 0.18%
U.S. 10yr
/quotes/zigman/15866666/realtime 2.16 +0.01 0.33%
German 10y
/quotes/zigman/15866409/realtime 0.80 +0.06 8.79%
Italy 10yr
/quotes/zigman/15866497/realtime 2.00 +0.08 4.05%
Spain 10yr
/quotes/zigman/15866444/realtime 2.14 +0.08 3.76%
U.K. 10yr
/quotes/zigman/15866328/realtime 1.83 -0.02 1.25%
Japan 10yr
/quotes/zigman/15866525/realtime 0.36 -0.02 4.88%
Crude Oil
/quotes/zigman/2331095/delayed 44 -1 2.77%
Gold
/quotes/zigman/662444/delayed 1,139 -1 0.10%
Corn
/quotes/zigman/7599553/delayed 368 -7 1.87%
DJIA F
/quotes/zigman/38649152/delayed 16,116 +29 0.18%
S&P F
/quotes/zigman/30356461/delayed 1,920 +4 0.19%
Silver
/quotes/zigman/3134148/delayed 15 0 0.27%

Quotes

Symbol Price Change % Change
FB /quotes/zigman/9962609/composite 87.23 -2.20 -2.46%
AAPL /quotes/zigman/68270/composite 107.72 -5.04 -4.47%
GOOG /quotes/zigman/30194416/composite 597.79 -20.46 -3.31%
BAC /quotes/zigman/190927/composite 15.58 -0.76 -4.65%
C /quotes/zigman/5065548/composite 50.94 -2.54 -4.75%
F /quotes/zigman/264304/composite 13.72 -0.15 -1.08%
T /quotes/zigman/398198/composite 32.32 -0.88 -2.65%
BP /quotes/zigman/247026/composite 32.14 -1.40 -4.17%
GE /quotes/zigman/227468/composite 23.88 -0.94 -3.79%
Visit the quote page and your most recently viewed stocks will automatically be displayed here.
Please log in to view your watchlist
MarketWatch Portfolio

World News from MarketWatch

Rates »

5 yr CD
1.5%
2 yr CD
0.8%
1 yr CD
0.6%
MMA $10K+
0.3%
MMA $50K+
0.4%

National averages from Bankrate.com

You Don’t Need Another Credit Card, You Need A Better One.
Avg. APR Last Week 6 Months
Low Interest 11.62% 11.62% 11.53%
Business 12.85% 12.85% 12.85%
Student 13.14% 13.14% 13.14%
Balance Transfer 14.12% 14.12% 14.00%
Airline 15.10% 15.10% 15.15%
Reward 15.14% 15.14% 14.99%
Cash Back 15.27% 15.27% 15.26%
Instant Approval 18.00% 18.00% 17.93%
Bad Credit 22.73% 22.73% 22.48%
Source:CreditCards.com

SPONSORED SECTIONS

Trending Tickers
  • /quotes/zigman/12221594/composite AMBA-6.30%
  • /quotes/zigman/8669138/composite DWTI+19.53%
  • /quotes/zigman/219890/composite HRB-3.15%
  • /quotes/zigman/4534424/composite QIHU-6.26%
  • /quotes/zigman/221038/composite CVC+1.95%
X
Powered by StockTwits
Link to MarketWatch's Slice.

As of July 2, 2013, the SmartMoney content you loved now lives on MarketWatch.

MarketWatch will continue to provide the same important news and information you rely on every day. And, as a MarketWatch user, you will be able to enjoy:

  • Personalized news and quote email alerts
  • Editorial e-newsletters about personal finance, mutual funds and market-specific coverage
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